Abstract:

Objective To analyze the brain structure and central mechanism of temporo mandibular disorders（TMD）under MRI examination. Methods 12 patients with TMD were selected as TMD group，and 12 healthy people matched with TMD patients were selected as healthy group.Two groups of patients completed the self rating scale，TMD patients received visual analog score，all subjects received brain magnetic resonance examina⁃ tion，analysis of the two groups of patients with brain regional consistency and functional connectivity，in order to analyze the correlation between TMD pain and brain central mechanism. Results The local consistency analysis showed that the ReHo value in the open state was higher than that in the closed state，and the difference was statistically significant（P < 0.05），the ReHo value of the two groups in the open state was statistically significant （P < 0.05）. Functional connectivity analysis showed that the two functional connectivity of TMD group were lower than that of healthy group，the difference was statistically significant（P < 0.05），And it is related to the intensity of pain. Conclusion TMD related pain is related to the local activity consistency of important brain regions，and also related to the abnormal functional connection between the related brain regions. In addition，the main reason for the abnormality of the related brain regions is psychological factors.

Key words:

temporomandibular disorders, magnetic resonance imaging, central mechanism, local consistency, function connection